The narrative follows young ninjas Naruto Uzumaki and Sasuke Uchiha as they participate in a global shinobi conflict—the Fourth Shinobi World War—against the terrorist organization Akatsuki and join forces to defeat it. Similar to Storm 3, the game uses standard fighting mechanics; however, players can switch between a team of three fighters who can assist one another. Other returning elements include boss battles—requiring quick-time events to access hidden cutscenes—and hack-and-slashsequences. The expanded version is titled Naruto Shippuden: Ultimate Ninja Storm 4 - Road to Boruto; this version was bundled with three other titles in the series, such as Naruto Shippuden: Ultimate Ninja Storm Legacy , and released in August 2017. It adds new characters from the 2015 film Boruto: Naruto the Movieas well as adult versions of the younger fighters.

The game was developed for PlayStation 4 and Xbox One over a two-year period. CyberConnect2 leveraged the hardware's potential to incorporate more combat mechanics and add new fighters. The game received generally positive reviews, according to Metacritic; its narrative and graphics were praised, though critics were divided regarding the story's length and the depth of the controls. In April 2020, a port for Nintendo Switch racing Naruto Shippuden: Ultimate Ninja Storm 4 - Road to Borutowas released. Including Road to Boruto, the game had sold 8.7 million copies by December 2021.